Structure of PDB 4ez1 Chain E

Receptor sequence
>4ez1E (length=202) Species: 6500 (Aplysia californica) [Search protein sequence]
SQANLMRLKSDLFMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYY
EQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQ
IAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEID
LKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFR
ER
3D structure
PDB4ez1 Pairwise interaction of alpha-conotoxin BuIA Pro6 with the beta subunit of nicotinic acetylcholine receptor
ChainE
Resolution2.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E Y55 V108 M116 I118 D164 S167 Y50 V103 M111 I113 D159 S162
BS02 peptide E S146 W147 Y149 Y188 C191 E193 Y195 S141 W142 Y144 Y183 C186 E188 Y190
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4ez1, PDBe:4ez1, PDBj:4ez1
PDBsum4ez1
PubMed
UniProtQ8WSF8

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