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BioLiP

Structure of PDB 6x8l Chain D

Receptor sequence
>6x8lD (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
KIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQI
LTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFS
3D structure
PDB6x8l Caspase-7 in complex with elongated ketomethylene inhibitor
ChainD
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D Y230 S231 W232 R233 P235 Q276 Y19 S20 W21 R22 P24 Q65
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6x8l, PDBe:6x8l, PDBj:6x8l
PDBsum6x8l
PubMed
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

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