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BioLiP

Structure of PDB 6wbf Chain D

Receptor sequence
>6wbfD (length=344) Species: 9606 (Homo sapiens) [Search protein sequence]
AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLIS
LAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNL
PLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYN
RAIKAAKSARDFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACI
YLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVI
NLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLS
LYNLFLEENISEVKSYKCLKVLENIKSSGQGIDPMLLLTNLGMI
3D structure
PDB6wbf Structures of human pannexin 1 reveal ion pathways and mechanism of gating.
ChainD
Resolution2.83 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR D I229 S236 I200 S207
Gene Ontology
Molecular Function
GO:0015267 channel activity
Biological Process
GO:0006812 monoatomic cation transport
GO:0032732 positive regulation of interleukin-1 production

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Molecular Function
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Biological Process
External links
PDB RCSB:6wbf, PDBe:6wbf, PDBj:6wbf
PDBsum6wbf
PubMed32494015
UniProtQ96RD7|PANX1_HUMAN Pannexin-1 (Gene Name=PANX1)

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