Structure of PDB 4z7q Chain D

Receptor sequence
>4z7qD (length=471) Species: 9606 (Homo sapiens) [Search protein sequence]
GPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCA
PESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNF
SIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLR
IGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQV
TRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTT
DAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLS
QKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGK
IRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIE
AKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNN
GNGTFECGVCRCGPGWLGSQC
3D structure
PDB4z7q beta-Subunit Binding Is Sufficient for Ligands to Open the Integrin alpha IIb beta 3 Headpiece.
ChainD
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D S121 Y122 S123 N215 A218 E220 S121 Y122 S123 N215 A218 E220
BS02 MN D D126 D127 M335 D126 D127 M335
BS03 MN D D158 N215 D217 P219 E220 D158 N215 D217 P219 E220
BS04 MN D S121 S123 E220 S121 S123 E220
External links
PDB RCSB:4z7q, PDBe:4z7q, PDBj:4z7q
PDBsum4z7q
PubMed26631735
UniProtP05106|ITB3_HUMAN Integrin beta-3 (Gene Name=ITGB3)

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