BioLiP

Structure of PDB 1ct8 Chain D

Receptor sequence

>1ct8D (length=220) Species: 10090 (Mus musculus) [Search protein sequence]

QVKLLESGAVLVKPGASVKLSCKTSGFTFSSSYINWLKQKPGQSLEWIAW
IYAGSGGTVYNQHFTDKARLTVDTSSSTAYMQFSSLTTEDSAIYYCARYR
YDEGFAYWGQGTLVTVSAAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGY
FPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTC
NVAHPASSTKVDKKIVPRDC

3D structure

PDB

1ct8 Diverse structural solutions to catalysis in a family of antibodies.

Chain

Resolution

2.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	TAA	D	S54 G56	S55 G57	MOAD: Kd=0.3uM PDBbind-CN: -logKd/Ki=6.52,Kd=0.3uM
BS02	TAA	D	Y33 N35 W50 Y95 Y97 F100A	Y33 N35 W50 Y99 Y101 F105	MOAD: Kd=0.3uM PDBbind-CN: -logKd/Ki=6.52,Kd=0.3uM

External links

PDB	RCSB:1ct8, PDBe:1ct8, PDBj:1ct8
PDBsum	1ct8
PubMed	10574796
UniProt	P01868\|IGHG1_MOUSE Ig gamma-1 chain C region secreted form (Gene Name=Ighg1)

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