BioLiP

Structure of PDB 8s8e Chain C

Receptor sequence

>8s8eC (length=220) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence]

EEKGWVPVTKLGRLVKAGKISSIEEIFLHSLPVKEFQIIDQLLPNLKDEV
MNIKPVQKQTRAGQRTRFKAVVVVGDSNGHVGLGIKTAKEVAGAIRAGII
IAKLSVIPIRRGYWGTNLGQPHSLATKTSGKCGSVSVRLIPAPRGSGIVA
SPAVKKLMQLAGVEDVYTSSTGSTRTLENTLKAAFVAIGNTYGFLTPNLW
EVQALTPSPMDVYADYATAS

3D structure

PDB

8s8e Structural basis of AUC codon discrimination during translation initiation in yeast.

Chain

Resolution

3.85 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	C	V91 Q92 K93 Q94 R96 A97 R100 K104 S164 K166 C167 G168 S169 R173 V184 A185 S186 Y202 T203 S205 T206 S208 T209 R210 T211 E213 N214 F229	V56 Q57 K58 Q59 R61 A62 R65 K69 S129 K131 C132 G133 S134 R138 V149 A150 S151 Y167 T168 S170 T171 S173 T174 R175 T176 E178 N179 F194
BS02	rna	C	I88 F103 V126	I53 F68 V91

External links

PDB	RCSB:8s8e, PDBe:8s8e, PDBj:8s8e
PDBsum	8s8e
PubMed	39193907
UniProt	Q6CKL3

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