BioLiP

Structure of PDB 5itv Chain C

Receptor sequence

>5itvC (length=255) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]

MIMNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRK
ENNDRLHFVQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHE
MELSDWNKVLQVNLTGMFLMSKHALKHMLAAGKGNIINTCSVGGLVAWPD
IPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCPGIIDTPLNEKSFLENN
EGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYMTGSAITADG
GYTAQ

3D structure

PDB

5itv Probing the influence of non-covalent contact networks identified by charge density analysis on the oxidoreductase BacC.

Chain

Resolution

2.26 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	G18 S141 Y154 K158
Catalytic site (residue number reindexed from 1)	G18 S141 Y154 K158
Enzyme Commision number	1.1.1.385: dihydroanticapsin 7-dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAI	C	G14 S17 G18 I19 D38 I39 T61 I63 N89 G91 T139 S141 Y154 K158 P184 G185 I186 I187 T189	G14 S17 G18 I19 D38 I39 T61 I63 N89 G91 T139 S141 Y154 K158 P184 G185 I186 I187 T189

Gene Ontology

	Molecular Function
GO:0016491	oxidoreductase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

	Biological Process
GO:0017000	antibiotic biosynthetic process

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Molecular Function

View graph for
Biological Process

PDB	RCSB:5itv, PDBe:5itv, PDBj:5itv
PDBsum	5itv
PubMed	28158843
UniProt	P39640\|BACC_BACSU Dihydroanticapsin 7-dehydrogenase (Gene Name=bacC)