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Structure of PDB 4zcf Chain C

Receptor sequence
>4zcfC (length=627) Species: 562 (Escherichia coli) [Search protein sequence]
TLEKNLPHQKAGVDAVMNVFVSATPHLTDNVAVRLLANPELKLSEQQYYN
NIKNVQAFNGIAHSKDNHNAKSNIIDVSMETGTGKTYTYIKTIFDLNKSF
GINKFIIIVPTLSIKAGTVNFLKSDALKEHFRDDYKRELRTYVVESQKMP
QAIHDFVEASNFKKYIHVLVINSGMINSKSLTDTYDTGLLDNQFNTPVDA
LRAVKPFIIIDEPHRFPTGKKTWENIEKFNAQYIIRYGATFSEGYKNLVY
RLTAVDAFNDDLVKGIDAYIEDNANLKFVKDGKEATFFKLAKSLSKTHSA
IHDLTLDALNTAVLSNGIELKIGSSINPYSYDQTLADNMMRKAVKEHFKL
EKELLTQPRIKPLTLFFIDDLKTKFEEYVLAEANELLYKNYLEKTVTNIS
SVHGGYIEQEINEILHDKELLLSLDNPRRFIFSKWTLREGWDNPNVFQIC
KLRSSKLQEVGRGLRLPVNEYMCRVKNFTLKYYVDFTEKDFVDSLVKEVN
ESSPSKFTQELKEQIDNFKDSDAYSRLKSELKELWDLINQKAVIEYKINS
ESEFLSIFKSFMLEETERSYREFLDNLSQTIFVKHGTLHKVFCDIKDTIL
NIQTIRKIKSGFSKYLLNNSFSLGYNL
3D structure
PDB4zcf Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I.
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.5: type III site-specific deoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C N192 R230 K235 K236 T237 N177 R215 K220 K221 T222
BS02 dna C T116 L117 S151 N187 G189 M190 S193 K194 G352 I353 E354 T111 L112 S146 N172 G174 M175 S178 K179 G317 I318 E319
BS03 AMP C T91 I119 G122 F126 D226 R537 T86 I114 G117 F121 D211 R465
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0004519 endonuclease activity
GO:0005524 ATP binding
GO:0015668 type III site-specific deoxyribonuclease activity
GO:0016787 hydrolase activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:4zcf, PDBe:4zcf, PDBj:4zcf
PDBsum4zcf
PubMed26067164
UniProtQ5ZND2|T3RE_ECOLX Type III restriction-modification enzyme EcoP15I Res subunit (Gene Name=res)

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