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Structure of PDB 4xgz Chain C

Receptor sequence

>4xgzC (length=219) Species: 9606 (Homo sapiens)

EVQLVESGGGLVQPGGSLRLSCAASGFNVSYSSIHWVRQAPGKGLEWVAS
IYSYYGYTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARGY
YGAAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSGTAALGCLVKDYFPE
PVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNV
NHKPSNTKVDKKVEPKSCD

3D structure

• PDB: 4xgz Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
• Chain: C
• Resolution: 2.5 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	C	Y31 S33 Y52 Y53 Y54 Y56 Y58 Y96 Y97 A99	Y31 S33 Y52 Y54 Y55 Y57 Y59 Y100 Y101 A103

External links

• PDB: RCSB:4xgz, PDBe:4xgz, PDBj:4xgz
• PDBsum: 4xgz
• PubMed: 26087144

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