BioLiP

Structure of PDB 4mo5 Chain C

Receptor sequence

>4mo5C (length=351) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]

PRYLGLMSGTSLDGMDIVLIEQGDRTTLLASHYLPMPAGLREDILALCVP
GPDEIARAAEVEQRWVALAAQGVRELLLQQQMSPDEVRAIGSHGQTIRHE
PARHFTVQIGNPALLAELTGIDVVADFRRRDVAAGGQGAPLVPAFHQALF
GDDDTSRAVLNIGGFSNVSLLSPGKPVRGFDCGPGNVLMDAWIHHQRGEH
FDRDGAWAASGQVNHALLASLLADEFFFNLPWLQEHLARHPALPAADIQA
TLLELSARSISESLLDAQPDCEEVLVCGGGAFNTALMKRLAMLMPEARVA
STDEYGIPPAWMEGMAFAWLAHRFLERLPGNCPDVTGALGPRTLGALYPA
G

3D structure

PDB

4mo5 Conformational Itinerary of Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase during Its Catalytic Cycle.

Chain

Resolution

1.75 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.7.1.170: anhydro-N-acetylmuramic acid kinase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	AH0	C	T97 H100 R129 P141 L142 V143	T96 H99 R128 P140 L141 V142
BS02	ACP	C	G164 N187 D191 F202 R204 D205 G292 F295 N296	G163 N186 D190 F201 R203 D204 G279 F282 N283

Gene Ontology

	Molecular Function
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016773	phosphotransferase activity, alcohol group as acceptor

	Biological Process
GO:0006040	amino sugar metabolic process
GO:0009254	peptidoglycan turnover
GO:0016310	phosphorylation
GO:0046677	response to antibiotic
GO:0097175	1,6-anhydro-N-acetyl-beta-muramic acid catabolic process

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Molecular Function

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Biological Process

PDB	RCSB:4mo5, PDBe:4mo5, PDBj:4mo5
PDBsum	4mo5
PubMed	24362022
UniProt	Q9I5Q5\|ANMK_PSEAE Anhydro-N-acetylmuramic acid kinase (Gene Name=anmK)