Structure of PDB 4hsn Chain C

Receptor sequence
>4hsnC (length=341) Species: 122586 (Neisseria meningitidis MC58) [Search protein sequence]
IKIKEVKELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVI
IGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGL
INDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLI
SWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSH
HFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAG
VTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVE
GRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMARA
3D structure
PDB4hsn Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine.
ChainC
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN C C63 H270 E304 D324 C54 H261 E295 D315
BS02 PEP C R94 A166 R167 K188 R236 H270 R85 A157 R158 K179 R227 H261
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4hsn, PDBe:4hsn, PDBj:4hsn
PDBsum4hsn
PubMed23754471
UniProtQ9K169

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