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Structure of PDB 4ez1 Chain C

Receptor sequence
>4ez1C (length=207) Species: 6500 (Aplysia californica) [Search protein sequence]
DDDKLHSQANLMRLKSDLFYPGPTKDDPLTVTLGFTLQDIVKADSSTNEV
DLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQ
VLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYS
GFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNL
VVKFRER
3D structure
PDB4ez1 Pairwise interaction of alpha-conotoxin BuIA Pro6 with the beta subunit of nicotinic acetylcholine receptor
ChainC
Resolution2.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C S146 W147 V148 Y149 Y188 C191 E193 Y195 S146 W147 V148 Y149 Y188 C191 E193 Y195
BS02 peptide C V108 M116 I118 S167 V108 M116 I118 S167
BS03 MN C D-3 H1 D2 H6
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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