BioLiP

Structure of PDB 2gvq Chain C

Receptor sequence

>2gvqC (length=341) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]

MNINEILKKLINKSDLEINEAEELAKAIIRGEVPEILVSAILVALRMKGE
SKNEIVGFARAMRELAIKIDVPNAIDTAGGLGTVNVSTASAILLSLVNPV
AKHGNRAVSGKSGSADVLEALGYNIIVPPERAKELVNKTNFVFLFAQYYH
PAMKNVANVRKTLGIRTIFNILGPLTNPANAKYQLMGVFSKDHLDLLSKS
AYELDFNKIILVYGEPGIDEVSPIGNTFMKIVSKRGIEEVKLNVTDFGIS
PIPIEKLIVNSAEDSAIKIVRAFLGKDEHVAEFIKINTAVALFALDRVGD
FREGYEYADHLIEKSLDKLNEIISMNGDVTKLKTIVVKSSG

3D structure

PDB

2gvq Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus.

Chain

Resolution

2.43 Å

3D
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Enzymatic activity

Enzyme Commision number

2.4.2.18: anthranilate phosphoribosyltransferase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	BE2	C	H107 G177	H103 G173
BS02	BE2	C	N109 H154 M157 R164	N105 H150 M153 R160

Gene Ontology

	Molecular Function
GO:0000287	magnesium ion binding
GO:0004048	anthranilate phosphoribosyltransferase activity
GO:0016757	glycosyltransferase activity
GO:0016763	pentosyltransferase activity
GO:0046872	metal ion binding

	Biological Process
GO:0000162	tryptophan biosynthetic process

	Cellular Component
GO:0005829	cytosol

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Molecular Function

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Cellular Component

PDB	RCSB:2gvq, PDBe:2gvq, PDBj:2gvq
PDBsum	2gvq
PubMed	16714288
UniProt	P50384\|TRPD_SACS2 Anthranilate phosphoribosyltransferase (Gene Name=trpD)