BioLiP

Structure of PDB 1n8f Chain C

Receptor sequence

>1n8fC (length=343) Species: 562 (Escherichia coli) [Search protein sequence]

LRIKEIKELLPPVALLQKFPATENAANTVAHARKAIHKILKGNDDRLLVV
IGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTVGWKGL
INDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLM
SWGAIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPH
CFLSVTKWGHSAIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEGLNKAG
LPAQVMIDFSHANSSKQFKKQMDVCADVCQQIAGGEKAIIGVMVESHLVE
GNQSLESGEPLAYGKSITDACIGWEDTDALLRQLANAVKARRG

3D structure

PDB

1n8f The High-Resolution Structure of 3-Deoxy-D-arabino-heptulosonate-7-phosphate Synthase Reveals a Twist in the Plane of Bound Phosphoenolpyruvate

Chain

Resolution

1.75 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MN	C	C61 H268 E302 D326	C54 H261 E295 D319
BS02	PEP	C	R92 K97 G163 K186 R234 H268	R85 K90 G156 K179 R227 H261

Gene Ontology

	Molecular Function
GO:0003849	3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740	transferase activity
GO:0042802	identical protein binding

	Biological Process
GO:0008652	amino acid biosynthetic process
GO:0009058	biosynthetic process
GO:0009073	aromatic amino acid family biosynthetic process
GO:0009423	chorismate biosynthetic process

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol

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Molecular Function

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Biological Process

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Cellular Component

PDB	RCSB:1n8f, PDBe:1n8f, PDBj:1n8f
PDBsum	1n8f
PubMed	12667068
UniProt	P0AB91\|AROG_ECOLI Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (Gene Name=aroG)