Structure of PDB 1n8f Chain C

Receptor sequence
>1n8fC (length=343) Species: 562 (Escherichia coli) [Search protein sequence]
LRIKEIKELLPPVALLQKFPATENAANTVAHARKAIHKILKGNDDRLLVV
IGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTVGWKGL
INDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLM
SWGAIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPH
CFLSVTKWGHSAIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEGLNKAG
LPAQVMIDFSHANSSKQFKKQMDVCADVCQQIAGGEKAIIGVMVESHLVE
GNQSLESGEPLAYGKSITDACIGWEDTDALLRQLANAVKARRG
3D structure
PDB1n8f The High-Resolution Structure of 3-Deoxy-D-arabino-heptulosonate-7-phosphate Synthase Reveals a Twist in the Plane of Bound Phosphoenolpyruvate
ChainC
Resolution1.75 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN C C61 H268 E302 D326 C54 H261 E295 D319
BS02 PEP C R92 K97 G163 K186 R234 H268 R85 K90 G156 K179 R227 H261
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1n8f, PDBe:1n8f, PDBj:1n8f
PDBsum1n8f
PubMed12667068
UniProtP0AB91|AROG_ECOLI Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (Gene Name=aroG)

[Back to BioLiP]