Structure of PDB 1h88 Chain C

Receptor sequence
>1h88C (length=152) Species: 10090 (Mus musculus) [Search protein sequence]
GKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNP
ELIKGPWTKEEDQRVIKLVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHL
NPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNST
MR
3D structure
PDB1h88 Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter
ChainC
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna C K92 K128 Q129 E132 R133 H137 N179 N183 S187 K54 K90 Q91 E94 R95 H99 N141 N145 S149 PDBbind-CN: Kd=35.3nM
BS02 dna C K113 R114 W115 R131 N164 R165 W166 A167 K182 K75 R76 W77 R93 N126 R127 W128 A129 K144 PDBbind-CN: Kd=35.3nM
External links
PDB RCSB:1h88, PDBe:1h88, PDBj:1h88
PDBsum1h88
PubMed11792321
UniProtP06876|MYB_MOUSE Transcriptional activator Myb (Gene Name=Myb)

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