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Structure of PDB 1f7q Chain C

Receptor sequence
>1f7qC (length=115) Species: 11673 (Feline immunodeficiency virus) [Search protein sequence]
MIIEGDGILDKRSEDAGYDLLAAKEIHLLPGEVKVIPTGVKLMLPKGYWG
LIIGKSSIGSKGLDVLGGVIDEGYRGEIGVIMINVSRKSITLMERQKIAQ
LIILPCKHEVLEQGK
3D structure
PDB1f7q Structures of feline immunodeficiency virus dUTP pyrophosphatase and its nucleotide complexes in three crystal forms.
ChainC
Resolution2.26 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A416 K455 S457 D464 D471
Catalytic site (residue number reindexed from 1) A16 K55 S57 D64 D71
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DUT C K455 S456 S457 K55 S56 S57
BS02 DUT C G468 V469 I470 D471 Y474 G479 G68 V69 I70 D71 Y74 G79
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004170 dUTP diphosphatase activity
Biological Process
GO:0006226 dUMP biosynthetic process
GO:0046081 dUTP catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1f7q, PDBe:1f7q, PDBj:1f7q
PDBsum1f7q
PubMed10957629
UniProtP16088|POL_FIVPE Pol polyprotein (Gene Name=pol)

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