BioLiP

Structure of PDB 4v8z Chain Ba

Receptor sequence

>4v8zBa (length=148) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

PSRFTKTRKHRGHVSAGKGRIGKHRKHPGGRGMAGGQHHHRINMDKYHPG
YFGKVGMRYFHKQQAHFWKPVLNLDKLWTLIPEDKRDQYLKSASKETAPV
IDTLAAGYGKILGKGRIPNVPVIVKARFVSKLAEEKIRAAGGVVELIA

3D structure

PDB

4v8z Molecular architecture of a eukaryotic translational initiation complex.

Chain

Resolution

6.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Ba	P2 S3 R4 F5 K7 T8 R9 K10 R12 G13 H14 V15 S16 A17 G18 K19 G20 R21 I22 H25 R26 K27 H28 P29 G30 G31 R32 G33 M34 A35 G36 H39 H40 H41 R42 I43 N44 K47 Y52 F53 G54 K55 G57 M58 R59 Y60 F61 H62 K63 Q64 H67 N74 K77 K111 L113 G114 K115 R117 S131 K132 L133 A149	P1 S2 R3 F4 K6 T7 R8 K9 R11 G12 H13 V14 S15 A16 G17 K18 G19 R20 I21 H24 R25 K26 H27 P28 G29 G30 R31 G32 M33 A34 G35 H38 H39 H40 R41 I42 N43 K46 Y51 F52 G53 K54 G56 M57 R58 Y59 F60 H61 K62 Q63 H66 N73 K76 K110 L112 G113 K114 R116 S130 K131 L132 A148

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015934	large ribosomal subunit
GO:0022625	cytosolic large ribosomal subunit
GO:0043232	intracellular non-membrane-bounded organelle
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

PDB	RCSB:4v8z, PDBe:4v8z, PDBj:4v8z
PDBsum	4v8z
PubMed	24200810
UniProt	P02406\|RL28_YEAST Large ribosomal subunit protein uL15 (Gene Name=RPL28)