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Structure of PDB 9enk Chain B

Receptor sequence

>9enkB (length=528) Species: 76867 (Hebeloma cylindrosporum)

ERVGILGAGIGGLYSALILQSLDVPFEIIEASNRVGGRLFTHKFPNGGKY
DYYDVGAMRYPLPKSDDKGNYQPGVMQRVGQLFTYLGMHKQLIPYYFKSN
KSPGFQYFNGVRARIGEGSSFDAPALGINSSLIDIGVTKIVNDAVGPFAQ
ALFDDLQKHTTTGWDDMMKNDAYSTRSYFSFKYLPSPSFGLPSEHFSTRV
INWLETFDKSTGWYDRGLTETVLEAIAFGEVEVDWRCIDGGSHVLPDTIA
AFLHKKAFVMNASVTAIGLENPNKEDSPMVVVAGGQKRKYSHVISTLPLP
VLRTVDLKNSKLDIVQSNALRKLQYGPSIKIGILFKEPWWTTGQDKNGEK
FDLVGGQSYTDLPIRTVVYPSYGVNTNAPSNTLIASYCWTNDAERMGSLI
GTGAATYEEQLEHLVLSNLAAVHNTDYQYLKDRLVDVHSWDWNHNPLTMG
AFAFFGPGDFQDLYTSLNRPAANGKLHFAGEALSVRHAWVVGALDSAWRA
VYNYLYVTDPAKLPKFFELWGKNAEWFE

3D structure

• PDB: 9enk Crystal structure and enzyme engineering of the broad substrate spectrum L-amino acid oxidase 4 from the fungus Hebeloma cylindrosporum
• Chain: B
• Resolution: 2.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FDA	B	G71 G73 I74 G75 E94 A95 G101 R102 G120 A121 M122 R123 Y124 S333 V334 L367 W512 L517 F522 G550 E551 A558 W559 V560 A563	G7 G9 I10 G11 E30 A31 G37 R38 G56 A57 M58 R59 Y60 S263 V264 L297 W442 L447 F452 G480 E481 A488 W489 V490 A493
BS02	PHE	B	R123 W277 E288 F292 Y457 W459 A558 W559	R59 W213 E224 F228 Y387 W389 A488 W489

External links

• PDB: RCSB:9enk, PDBe:9enk, PDBj:9enk
• PDBsum: 9enk
• PubMed: 39152524
• UniProt: S4S6Z0

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