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BioLiP

Structure of PDB 9at3 Chain B

Receptor sequence
>9at3B (length=301) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search protein sequence]
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDML
NPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPK
YKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF
NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTI
TVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL
GPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC
S
3D structure
PDB9at3 Structure-Guided Design of Potent Coronavirus Inhibitors with a 2-Pyrrolidone Scaffold: Biochemical, Crystallographic, and Virological Studies.
ChainB
Resolution1.7 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1AGK B F140 N142 C145 H163 H164 M165 E166 P168 Q189 T190 A191 F140 N142 C145 H163 H164 M165 E166 P168 Q189 T190 A191
BS02 A1AGL B N142 C145 H163 H164 M165 E166 P168 Q189 T190 A191 N142 C145 H163 H164 M165 E166 P168 Q189 T190 A191
External links
PDB RCSB:9at3, PDBe:9at3, PDBj:9at3
PDBsum9at3
PubMed38953866
UniProtP0DTD1|R1AB_SARS2 Replicase polyprotein 1ab (Gene Name=rep)

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