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Structure of PDB 8va1 Chain B

Receptor sequence
>8va1B (length=560) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
VKSKIYIDKIYWERVQLFVEGHSENLDLEDSNFVLRNLTETRTMKANDVK
IDGNQFVCRFNVAILDNGYYLPEDKYLLVNEQELDYIAQLNPDVINDAYQ
NLKPEQEEEYNELETQNGKINFLLQTYLKEFRKGGISKKTVYTVTPEISS
DVNEFVLDVVVTTPEVKSIYIVRKYKELRKYFRKQSFNTRQFIFKAIFNT
TKFFHLKKGNTVLFTSDSRPTMSGNFEYIYNEMLRQNLDKKYDIHTVFKA
NITDRRGIIDKFRLPYLLGKADYIFVDDFHPLIYTVRFRRSQEVIQVWNA
VGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIKE
KNVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVILFAPTFRGSG
HGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNIADKHKQYFV
DVSDFREVNDILFITDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTR
DFYEPYESFVPGKIVQSFDALMDALDNEDYEGEKVIPFLDKHFKYQDGRS
SERLVRNLFG
3D structure
PDB8va1 Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance.
ChainB
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.8.14: CDP-ribitol ribitolphosphotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 V2V B W299 A301 G303 K306 V308 Y343 P395 K431 H433 V459 S474 S475 L476 E479 W298 A300 G302 K305 V307 Y342 P394 K430 H432 V458 S473 S474 L475 E478
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0047355 CDP-glycerol glycerophosphotransferase activity
GO:0047356 CDP-ribitol ribitolphosphotransferase activity
Biological Process
GO:0019350 teichoic acid biosynthetic process
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:8va1, PDBe:8va1, PDBj:8va1
PDBsum8va1
PubMed38416829
UniProtQ2G1B8|TARL_STAA8 Teichoic acid ribitol-phosphate polymerase TarL (Gene Name=tarL)

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