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BioLiP

Structure of PDB 5z96 Chain B

Receptor sequence
>5z96B (length=665) Species: 10090 (Mus musculus) [Search protein sequence]
RDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININ
CIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVEL
LLNHKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVDSLRH
SRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYE
ELSRQCKQFAKDLLDQTRSSRELEIILNYRDDLARLKLAIKYRQKEFVAQ
PNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKS
PLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDNRQGPPPTIVEWMIL
PWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV
KYSNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISL
GRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIRCEKQNN
AFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISL
VVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNV
IIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELK
QDISSFRFEVLGLLR
3D structure
PDB5z96 Structure of the mouse TRPC4 ion channel.
ChainB
Resolution3.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Y01 B W321 L374 F378 L495 F496 W268 L321 F325 L436 F437
BS02 Y01 B F521 L525 F462 L466
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005262 calcium channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:5z96, PDBe:5z96, PDBj:5z96
PDBsum5z96
PubMed30082700
UniProtQ9QUQ5|TRPC4_MOUSE Short transient receptor potential channel 4 (Gene Name=Trpc4)

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