BioLiP

Structure of PDB 4bqk Chain B

Receptor sequence

>4bqkB (length=422) Species: 4530 (Oryza sativa) [Search protein sequence]

SLPAMIGGVYSDDNNLQLEATTQFRKLLSIERSPPIEEVIQSGVVPRFVQ
FLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSD
DVREQAVWALGNVAGDSPKCRDLVLANGALLPLLAQLNEHTKLSMLRNAT
WTLSNFCRGKPQPSFEQTRPALPALARLIHSNDEEVLTDACWALSYLSDG
TNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQCI
IDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGNKDQIQAVINAGIIG
PLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPLCDLLI
CPDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIEN
LQSHDNNEIYEKAVKILEAYWM

3D structure

PDB

4bqk Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium Vird2 with Rice Importin-Alpha

Chain

Resolution

1.997 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	F134 W138 N142 A144 S145 G146 T147 S148 T151 Q177 W180 N184 G187 D188 W223 S226 N227 R230 R306 N310 V312 G314 E346 W349 N353 A356 E388 W391 N395	F62 W66 N70 A72 S73 G74 T75 S76 T79 Q105 W108 N112 G115 D116 W151 S154 N155 R158 R234 N238 V240 G242 E274 W277 N281 A284 E316 W319 N323

Gene Ontology

	Molecular Function
GO:0061608	nuclear import signal receptor activity

	Biological Process
GO:0006606	protein import into nucleus

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Cellular Component

PDB	RCSB:4bqk, PDBe:4bqk, PDBj:4bqk
PDBsum	4bqk
PubMed	24503158
UniProt	Q71VM4\|IMA1A_ORYSJ Importin subunit alpha-1a (Gene Name=Os01g0253300)