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BioLiP

Structure of PDB 3s90 Chain B

Receptor sequence
>3s90B (length=251) Species: 9606 (Homo sapiens) [Search protein sequence]
PVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAV
SNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYS
VPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVV
ETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL
LPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLT
S
3D structure
PDB3s90 Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin.
ChainB
Resolution1.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I12 V16 Q19 V47 A50 L54 V57 M74 L88 I115 L122 F126 I11 V15 Q18 V46 A49 L53 V56 M73 L87 I114 L121 F125
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005198 structural molecule activity
GO:0051015 actin filament binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0015629 actin cytoskeleton

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Cellular Component
External links
PDB RCSB:3s90, PDBe:3s90, PDBj:3s90
PDBsum3s90
PubMed21648001
UniProtP18206|VINC_HUMAN Vinculin (Gene Name=VCL)

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