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BioLiP

Structure of PDB 2jet Chain B

Receptor sequence
>2jetB (length=125) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVA
GEFDQGENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAV
CLPNVDDDFPPGTVCATTGWGKTKY
3D structure
PDB2jet The Crystal Structure of a Trypsin-Like Mutant Chymotrypsin: The Role of Position 226 in the Activity and Specificity of S189D Chymotrypsin.
ChainB
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H57 D102
Catalytic site (residue number reindexed from 1) H39 D81
Enzyme Commision number 3.4.21.1: chymotrypsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B E20 I23 S26 W27 P28 W29 E116 A120 C122 E2 I5 S8 W9 P10 W11 E95 A99 C101
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2jet, PDBe:2jet, PDBj:2jet
PDBsum2jet
PubMed17805946
UniProtP07338|CTRB1_RAT Chymotrypsinogen B (Gene Name=Ctrb1)

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