Structure of PDB 1tz6 Chain B

Receptor sequence
>1tz6B (length=297) Species: 99287 (Salmonella enterica subsp. enterica serovar Typhimurium str. LT2) [Search protein sequence]
NKVWVIGDASVDLVPEKQNSYLKCPGGASANVGVCVARLGGECGFIGCLG
DDDAGRFLRQVFQDNGVDVTFLRLDADLTSAVLIVNFTYLVHPGADTYVS
PQDLPPFRQYEWFYFSSIGLTDRPAREACLEGARRMREAGGYVLFDVNLR
SKMWGNTDEIPELIARSAALASICKVSADELCQLSGASHWQDARYYLRDL
GCDTTIISLGADGALLITAEGEFHFPAPRVDVVDTTGAGDAFVGGLLFTL
SRANCWDHALLAEAISNANACGAMAVTAKGAMTALPFPDQLNTFLSS
3D structure
PDB1tz6 Crystal Structure of an Aminoimidazole Riboside Kinase from Salmonella enterica; Implications for the Evolution of the Ribokinase Superfamily
ChainB
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C28 F99 G249 A250 G251 D252
Catalytic site (residue number reindexed from 1) C24 F87 G237 A238 G239 D240
Enzyme Commision number 2.7.1.223: aminoimidazole riboside kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACP B N160 S189 S220 G222 A223 G251 N281 N148 S177 S208 G210 A211 G239 N269
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008865 fructokinase activity
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0006000 fructose metabolic process
GO:0016310 phosphorylation
GO:0046835 carbohydrate phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1tz6, PDBe:1tz6, PDBj:1tz6
PDBsum1tz6
PubMed15458630
UniProtQ8ZKR2|AIRSK_SALTY Aminoimidazole riboside kinase (Gene Name=STM4066)

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