Structure of PDB 1my4 Chain B

Receptor sequence

>1my4B (length=259) Species: 10116 (Rattus norvegicus) [Search protein sequence]

NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYK
LTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDF
SKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKI
AVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQ
RKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKN
KWWYDKGEC

3D structure

PDB

1my4 Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal

Chain

Resolution

1.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	B	H23 E30	H21 E28
BS02	ZN	B	E42 H46	E40 H44
BS03	IWD	B	Y61 T91 R96 L138 G141 S142 T143 L192 E193 M196	Y59 T89 R94 L136 G139 S140 T141 L190 E191 M194	BindingDB: Ki=105nM

Gene Ontology

	Molecular Function
GO:0015276	ligand-gated monoatomic ion channel activity

	Cellular Component
GO:0016020	membrane

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Molecular Function

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Cellular Component

External links

PDB	RCSB:1my4, PDBe:1my4, PDBj:1my4
PDBsum	1my4
PubMed	12731861
UniProt	P19491\|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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