Structure of PDB 1hqr Chain B

Receptor sequence
>1hqrB (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
DTRPRFLQQDKYECHFFNGTERVRFLHRDIYNQEEDLRFDSDVGEYRAVT
ELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTVQRRVEPKVTV
YPAHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNGDWTFQTL
VMLETVPREVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB1hqr Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II.
ChainB
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B Y213 W261 F267 R271 Y278 N282 V285 Y12 W60 F66 R70 Y77 N81 V84
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:1hqr, PDBe:1hqr, PDBj:1hqr
PDBsum1hqr
PubMed11163233
UniProtQ30154|DRB5_HUMAN HLA class II histocompatibility antigen, DR beta 5 chain (Gene Name=HLA-DRB5)

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