Structure of PDB 1ebp Chain B

Receptor sequence
>1ebpB (length=211) Species: 9606 (Homo sapiens) [Search protein sequence]
KFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQL
EDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRY
HRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVD
VSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFW
SAWSEPVSLLT
3D structure
PDB1ebp Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S91 S92 F93 V94 S82 S83 F84 V85
BS02 peptide B L33 F93 P149 M150 T151 S152 L24 F84 P140 M141 T142 S143
Gene Ontology
Molecular Function
GO:0004896 cytokine receptor activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1ebp, PDBe:1ebp, PDBj:1ebp
PDBsum1ebp
PubMed8662530
UniProtP19235|EPOR_HUMAN Erythropoietin receptor (Gene Name=EPOR)

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