Structure of PDB 1cea Chain B

Receptor sequence
>1ceaB (length=80) Species: 9606 (Homo sapiens) [Search protein sequence]
ECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENY
CRNPDNDPQGPWCYTTDPEKRYDYCDILEC
3D structure
PDB1cea Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid.
ChainB
Resolution2.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.7: plasmin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACA B R34 F35 D54 D56 W61 Y63 R70 Y71 R35 F36 D55 D57 W62 Y64 R71 Y72 MOAD: Kd~11uM
PDBbind-CN: -logKd/Ki=4.96,Kd=11uM
BindingDB: Ki=53000000nM,Kd=9000nM,IC50=105000nM
External links
PDB RCSB:1cea, PDBe:1cea, PDBj:1cea
PDBsum1cea
PubMed8611560
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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