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Structure of PDB 8yfj Chain A

Receptor sequence

>8yfjA (length=143) Species: 9606 (Homo sapiens)

SWCLSVHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATAKKPSPQEVSE
LQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFKEQFPDISQES
DSPFVFICKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMK

3D structure

• PDB: 8yfj Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
• Chain: A
• Resolution: 1.84 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	T472 A473 K554 G555 N556 P557	T39 A40 K121 G122 N123 P124

External links

• PDB: RCSB:8yfj, PDBe:8yfj, PDBj:8yfj
• PDBsum: 8yfj
• PubMed: 38870938
• UniProt: Q15650|TRIP4_HUMAN Activating signal cointegrator 1 (Gene Name=TRIP4)

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