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BioLiP

Structure of PDB 8pxx Chain A

Receptor sequence
>8pxxA (length=99) Species: 9606 (Homo sapiens) [Search protein sequence]
GAMGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPW
KEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNL
3D structure
PDB8pxx Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline rich motifs
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y157 S166 T167 W168 Y198 S207 W209 Y20 S29 T30 W31 Y61 S70 W72
Gene Ontology
Biological Process
GO:0045292 mRNA cis splicing, via spliceosome

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Biological Process
External links
PDB RCSB:8pxx, PDBe:8pxx, PDBj:8pxx
PDBsum8pxx
PubMed38719828
UniProtO75400|PR40A_HUMAN Pre-mRNA-processing factor 40 homolog A (Gene Name=PRPF40A)

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