Structure of PDB 8dpo Chain A

Receptor sequence
>8dpoA (length=222) Species: 485 (Neisseria gonorrhoeae) [Search protein sequence]
THWGYTGHDSPESWGNLSEEFRLCSTGKNQSPVNITETVSGKLPAIKVNY
KPSMVDVENNGHTIQVNYPEGGNTLTVNGRTYTLKQFHFHVPSENQIKGR
TFPMEAHFVHLDENKQPLVLAVLYEAGKTNGRLSSIWNVMPMTAGKVKLN
QPFDASTLLPKRLKYYRFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKF
TRAVGSENNRPVQPLNARVVIE
3D structure
PDB8dpo Crystal structure of Neisseria gonorrhoeae carbonic anhydrase with Acetazolamide
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AZM A H92 H94 H111 L176 T177 H88 H90 H107 L172 T173
BS02 ZN A H92 H94 H111 H88 H90 H107
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0046872 metal ion binding
Cellular Component
GO:0042597 periplasmic space

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8dpo, PDBe:8dpo, PDBj:8dpo
PDBsum8dpo
PubMed
UniProtQ50940|CAH_NEIGO Carbonic anhydrase (Gene Name=cah)

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