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BioLiP

Structure of PDB 7ugi Chain A

Receptor sequence
>7ugiA (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
SMIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKS
PMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKL
SEVFEQEIDPVMQSLG
3D structure
PDB7ugi Structural basis of CBP and EP300 interaction with kinase inhibitors
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 N6I A W1115 W1122 W1129 E1150 M1157 W70 W77 W84 E105 M112
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7ugi, PDBe:7ugi, PDBj:7ugi
PDBsum7ugi
PubMed
UniProtQ09472|EP300_HUMAN Histone acetyltransferase p300 (Gene Name=EP300)

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