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Structure of PDB 7rnu Chain A

Receptor sequence

>7rnuA (length=107) Species: 9606 (Homo sapiens)

PPSLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRK
GGNNKLIKVFHRDGHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTRL
LYPVSKY

3D structure

• PDB: 7rnu The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin
• Chain: A
• Resolution: 1.45 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	R340 R358 A360 S361 T369 L380 Y416 N417	R16 R34 A36 S37 T45 L56 Y92 N93
BS02	peptide	A	H410 R423	H86 R99

External links

• PDB: RCSB:7rnu, PDBe:7rnu, PDBj:7rnu
• PDBsum: 7rnu
• UniProt: O00459|P85B_HUMAN Phosphatidylinositol 3-kinase regulatory subunit beta (Gene Name=PIK3R2)

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