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BioLiP

Structure of PDB 6xeu Chain A

Receptor sequence
>6xeuA (length=328) Species: 10090 (Mus musculus) [Search protein sequence]
IQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTV
TWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETT
IGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAET
LVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEF
IPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEEL
EIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYN
SFHETYETSTPSLSAKELAELANRAESN
3D structure
PDB6xeu Structural insights into GIRK2 channel modulation by cholesterol and PIP2
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 PIO A K90 W91 R92 K199 K36 W37 R38 K145
Gene Ontology
Molecular Function
GO:0005242 inward rectifier potassium channel activity
Biological Process
GO:0006813 potassium ion transport
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6xeu, PDBe:6xeu, PDBj:6xeu
PDBsum6xeu
PubMed
UniProtP48542|KCNJ6_MOUSE G protein-activated inward rectifier potassium channel 2 (Gene Name=Kcnj6)

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