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Structure of PDB 6tqs Chain A

Receptor sequence

>6tqsA (length=131) Species: 9606 (Homo sapiens)

KKPLSVFKGPLLHISPAEELYFGSTESGEKKTLIVLTNVTKNIVAFKVRT
TAPEKYRVKPSNSSCDPGASVDIVVSPHGGLTVSAQDRFLIMAAEMEQSS
GTGPAELTQFWKEVPRNKVMEHRLRCHTVES

3D structure

• PDB: 6tqs FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts.
• Chain: A
• Resolution: 2.25 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	V364 R365 T366 T367 P369 R373 V374 R404 L406 R439	V48 R49 T50 T51 P53 R57 V58 R88 L90 R123
BS02	TFA	A	G325 P326 L327 L328 M436 E437	G9 P10 L11 L12 M120 E121

External links

• PDB: RCSB:6tqs, PDBe:6tqs, PDBj:6tqs
• PDBsum: 6tqs
• PubMed: 33124732
• UniProt: Q8NHP6|MSPD2_HUMAN Motile sperm domain-containing protein 2 (Gene Name=MOSPD2)

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