BioLiP

Structure of PDB 6c3h Chain A

Receptor sequence

>6c3hA (length=393) Species: 316058 (Rhodopseudomonas palustris HaA2) [Search protein sequence]

TIPHLAIDPFSLDFFDDPYPDQQTLRDAGPVVYLDKWNVYGVARYAEVHA
VLNDPTTFCSSRGVGLSDFKKEKPWRPPSLILEADPPAHTRPRAVLSKVL
SPATMKTIRDGFAAAADAKVDELLQRGCIDAIADLAEAYPLSVFPDAMGL
KQEGREHLLPYAGLVFNAFGPPNELRQTAIERSAPHQAYVNEQCQRPNLA
PGGFGACIHAFTDTGEITPDEAPLLVRSLLSAGLDTTVNGIGAAVYCLAR
FPGELQRLRSDPTLARNAFEEAVRFESPVQTFFRTTTREVELGGAVIGEG
EKVLMFLGSANRDPRRWSDPDLYDITRKTSGHVGFGSGVHMCVGQLVARL
EGEVMLSALARKVAAIDIDGPVKRRFNNTLRGLESLPVKLTPA

3D structure

PDB

6c3h The crystal structure of 4-n-heptylbenzoate-bound CYP199A4

Chain

Resolution

1.705 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	N183 D251 T252 C358 V359 G360
Catalytic site (residue number reindexed from 1)	N167 D235 T236 C342 V343 G344
Enzyme Commision number	?

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	A	I97 L98 H105 R109 A248 G249 T252 F298 R300 G350 F351 H356 C358 V359 G360	I81 L82 H89 R93 A232 G233 T236 F282 R284 G334 F335 H340 C342 V343 G344
BS02	EJV	A	S95 L98 F182 F185 S244 A248 F298	S79 L82 F166 F169 S228 A232 F282

Gene Ontology

	Molecular Function
GO:0004497	monooxygenase activity
GO:0005506	iron ion binding
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037	heme binding
GO:0046872	metal ion binding

View graph for
Molecular Function

PDB	RCSB:6c3h, PDBe:6c3h, PDBj:6c3h
PDBsum	6c3h
PubMed
UniProt	Q2IU02