Structure of PDB 6a8b Chain A

Receptor sequence
>6a8bA (length=327) Species: 981087 (Leishmania donovani BPK282A1) [Search protein sequence]
RARNVRSHTGEYAPDILVVGSCFLDYVGYVDHMPQVGETMHSVSFHKGFG
GKGANQAVAAGRLGAKVAMVSMVGTDGDGSDYIKELERNGVDTAYMFRTG
KSSTGLAMILVDTKSSNNEIVICPNATNHFTPELLRAQTNNYERILHTGL
KYLICQNEIPLPTTLDTIKEAHSRGVYTVFNSAPAPKPAEVEQIKPFLPY
VSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVITLGAAGFV
LSENGAEPVHVTGKHVKAVDTTGAGDCFVGSMVYFMSRGRNLLEACKRAN
ECAAISVTRKGTQLSYPHPSELPAGVM
3D structure
PDB6a8b Unraveling structural insights of ribokinase from Leishmania donovani.
ChainA
Resolution2.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.15: ribokinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACP A G247 A248 T273 A276 G277 N302 A305 V309 G245 A246 T271 A274 G275 N300 A303 V307
BS02 GOL A D27 G52 G53 N57 D25 G50 G51 N55
BS03 GOL A N159 I161 E192 N157 I159 E190
Gene Ontology
Molecular Function
GO:0004747 ribokinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0006014 D-ribose metabolic process
GO:0016310 phosphorylation
GO:0019303 D-ribose catabolic process
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:6a8b, PDBe:6a8b, PDBj:6a8b
PDBsum6a8b
PubMed31170491
UniProtA0A3S7X0F5

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