Structure of PDB 5x54 Chain A

Receptor sequence
>5x54A (length=285) Species: 9606 (Homo sapiens) [Search protein sequence]
GRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLL
YAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGH
IYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYA
VGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGG
YDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDG
HTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
3D structure
PDB5x54 Discovery of a Kelch-like ECH-associated protein 1-inhibitory tetrapeptide and its structural characterization
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y334 S363 R380 R415 R483 S508 G509 Q530 S555 A556 Y572 F577 S602 Y10 S39 R56 R91 R159 S184 G185 Q206 S231 A232 Y248 F253 S278
External links
PDB RCSB:5x54, PDBe:5x54, PDBj:5x54
PDBsum5x54
PubMed28315327
UniProtQ14145|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)

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