Structure of PDB 5uvx Chain A

Receptor sequence
>5uvxA (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
HMEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMD
MSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDV
FEMRFAKM
3D structure
PDB5uvx BRD4 Bromodomain 2 with A-1359643
ChainA
Resolution1.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8NM A W374 P375 K378 P379 V380 L385 L387 N433 H437 V439 M442 W25 P26 K29 P30 V31 L36 L38 N84 H88 V90 M93 BindingDB: Ki=2.4nM,EC50=11nM
External links
PDB RCSB:5uvx, PDBe:5uvx, PDBj:5uvx
PDBsum5uvx
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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