BioLiP

Structure of PDB 5qpo Chain A

Receptor sequence

>5qpoA (length=360) Species: 5693 (Trypanosoma cruzi) [Search protein sequence]

MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYF
RGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDI
MDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLK
DLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIY
KRIVKYKTTFYTYLLPLVMGLLVSEAAASVEMNLVERVAHLIGEYFQVQD
DVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGEK
DPAKVAVVKRLYSKANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESV
AVVWEKTHKR

3D structure

PDB

5qpo PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library

Chain

Resolution

1.6 Å

3D
structure

Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Catalytic site (original residue number in PDB)	K48 H93 D98 D102 R107 D170 K207 F246 D250 D251
Catalytic site (residue number reindexed from 1)	K48 H93 D98 D102 R107 D170 K207 F246 D250 D251
Enzyme Commision number	?

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GQP	A	K158 F210	K158 F210

Gene Ontology

	Molecular Function
GO:0004659	prenyltransferase activity
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups

	Biological Process
GO:0008299	isoprenoid biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process

PDB	RCSB:5qpo, PDBe:5qpo, PDBj:5qpo
PDBsum	5qpo
PubMed
UniProt	Q8WS26