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BioLiP

Structure of PDB 4hx1 Chain A

Receptor sequence
>4hx1A (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTSMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDRNTRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQRMYG
CDVGPDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQWRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVP
SGQEQRYTCHVQHEGLPKPLTLKW
3D structure
PDB4hx1 Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
ChainA
Resolution1.802 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 Y9 N63 N66 A69 Q70 T73 V76 D77 L81 Y99 Y116 T143 K146 W147 Q155 W156 Y159 W167 Y171 Y7 Y9 N63 N66 A69 Q70 T73 V76 D77 L81 Y99 Y116 T143 K146 W147 Q155 W156 Y159 W167 Y171
External links
PDB RCSB:4hx1, PDBe:4hx1, PDBj:4hx1
PDBsum4hx1
PubMed23566939
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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