Structure of PDB 4gv6 Chain A

Receptor sequence
>4gv6A (length=207) Species: 11622 (Lassa virus Josiah) [Search protein sequence]
GAMDHVEFGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQP
SSGCYIHFFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPR
NMVITCQGSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDL
CHMHTGVVVEKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFR
TSPRVVL
3D structure
PDB4gv6 Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
ChainA
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A E391 G392 D426 S430 Q462 D466 S487 K488 E36 G37 D71 S75 Q107 D111 S132 K133
BS02 rna A R393 Q425 Y429 R38 Q70 Y74
BS03 ZN A E399 C506 H509 C529 E44 C151 H154 C168
External links
PDB RCSB:4gv6, PDBe:4gv6, PDBj:4gv6
PDBsum4gv6
PubMed23615902
UniProtP13699|NCAP_LASSJ Nucleoprotein (Gene Name=N)

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