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Structure of PDB 4cvl Chain A

Receptor sequence
>4cvlA (length=426) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
MLEPLRLSQLTVALDARLIGEDAVFSAVSTDSRAIGPGELFIALSDGHDY
LAEVAAKGAVAALVEREAPLPQLLVRDTRAALGRLGALNRRKFTGPLAAM
TGSSGKTTVKEMLASILRTQAGDAESVLATRGNLNNDLGVPLTLLQLAPQ
HRSAVIELGASRIGEIAYTVELTRPHVAIITNAGPEKIVEAKGEILEGLA
ADGTAVLNLDDKAFDTWKARASGRPLLTFSLDRPQADFRAADLQRDARGC
MGFRLQGVAGEAQVQLNLLGRHNVANALAAAAAAHALGVPLDGIVAGLQA
LQPVKGRAVAQLTASGLRVIDDSPASMLAAIDILSGFSGRTVLVLGDMGA
EQAHREVGAYAAGKVSALYAVGPLMAHAVQAFGATGRHFADQASLIGALA
TEDPTTTILIKGSRSAAMDKVVAALC
3D structure
PDB4cvl Pamurf in Complex with AMP-Pnp
ChainA
Resolution2.98 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K113 T114 D144 E164
Catalytic site (residue number reindexed from 1) K106 T107 D137 E157
Enzyme Commision number 6.3.2.10: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACP A S111 G112 K113 T114 T115 N140 N189 H288 S104 G105 K106 T107 T108 N133 N182 H272
BS02 MG A T114 N140 E164 T107 N133 E157
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008766 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
GO:0016874 ligase activity
GO:0016881 acid-amino acid ligase activity
GO:0046872 metal ion binding
GO:0047480 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009058 biosynthetic process
GO:0009252 peptidoglycan biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
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