Structure of PDB 3zxt Chain A

Receptor sequence
>3zxtA (length=249) Species: 9606 (Homo sapiens) [Search protein sequence]
ENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTREDIERE
VSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEE
EATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRVPKPRIKIIDFGLA
HKIDEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLA
NVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK
3D structure
PDB3zxt A Journey Through the Dap Kinase Architecture
ChainA
Resolution2.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D139 K141 E143 N144 D161
Catalytic site (residue number reindexed from 1) D125 K127 E129 N130 D146
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACP A G22 Q23 V27 A40 K42 I77 V96 E100 E143 M146 I160 D161 G16 Q17 V21 A34 K36 I63 V82 E86 E129 M132 I145 D146
BS02 MG A N144 D161 N130 D146
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3zxt, PDBe:3zxt, PDBj:3zxt
PDBsum3zxt
PubMed
UniProtP53355|DAPK1_HUMAN Death-associated protein kinase 1 (Gene Name=DAPK1)

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