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Structure of PDB 2fyg Chain A

Receptor sequence
>2fygA (length=128) [Search protein sequence]
HHHHHNSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQA
ITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCA
NDPVGFTLRNTVCTVCGMWKGYGCSCDQ
3D structure
PDB2fyg Crystal structure of nonstructural protein 10 from the severe acute respiratory syndrome coronavirus reveals a novel fold with two zinc-binding motifs.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.50: mRNA guanylyltransferase.
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.4.22.69: SARS coronavirus main proteinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C74 C77 H83 C90 C70 C73 H79 C86
BS02 ZN A C117 C120 C128 C130 C113 C116 C124 C126
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0019079 viral genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2fyg, PDBe:2fyg, PDBj:2fyg
PDBsum2fyg
PubMed16873246
UniProtP0C6U8|R1A_SARS Replicase polyprotein 1a (Gene Name=1a)

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