Structure of PDB 2abs Chain A

Receptor sequence
>2absA (length=340) Species: 5811 (Toxoplasma gondii) [Search protein sequence]
TGPMRVFAIGNPILDLVAEVPSSFLDEFFLKRGDATLATPEQMRIYSTLD
QFNPTSLPGGSALNSVRVVQKLLRKPGSAGYMGAIGDDPRGQVLKELCDK
EGLATRFMVAPGQSTGVCAVLINEKERTLCTHLGACGSFRLPEDWTTFAS
GALIFYATAYTLTATPKNALEVAGYAHGIPNAIFTLNLSAPFCVELYKDA
MQSLLLHTNILFGNEEEFAHLAKVHNLVNKEHAVEVCTGALRLLTAGQNT
SATKLVVMTRGHNPVIAAEQTADGTVVVHEVGVPVVAAEKIVDTNGAGDA
FVGGFLYALSQGKTVKQCIMCGNACAQDVIQHVGFSLSFT
3D structure
PDB2abs Structure of Toxoplasma gondii adenosine kinase in complex with an ATP analog at 1.1 angstroms resolution.
ChainA
Resolution1.1 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) R136 G315 A316 G317 D318
Catalytic site (residue number reindexed from 1) R127 G296 A297 G298 D299
Enzyme Commision number 2.7.1.20: adenosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACP A T278 G280 H281 V302 T313 N342 A345 T259 G261 H262 V283 T294 N323 A326
Gene Ontology
Molecular Function
GO:0004001 adenosine kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0006166 purine ribonucleoside salvage
GO:0016310 phosphorylation
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0044209 AMP salvage
GO:0055086 nucleobase-containing small molecule metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2abs, PDBe:2abs, PDBj:2abs
PDBsum2abs
PubMed16421444
UniProtQ9TVW2|ADK_TOXGO Adenosine kinase (Gene Name=AK)

[Back to BioLiP]