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Structure of PDB 1t74 Chain A

Receptor sequence
>1t74A (length=249) Species: 9598 (Pan troglodytes) [Search protein sequence]
QPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWA
KALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLV
FNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVD
GLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPI
ARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
3D structure
PDB1t74 Recognition and accommodation at the androgen receptor coactivator binding interface.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L712 V716 K720 M734 I737 Q738 E893 M894 L43 V47 K51 M65 I68 Q69 E224 M225
BS02 DHT A L701 L704 N705 Q711 M745 M749 F764 T877 L32 L35 N36 Q42 M76 M80 F95 T208
External links
PDB RCSB:1t74, PDBe:1t74, PDBj:1t74
PDBsum1t74
PubMed15328534
UniProtO97775|ANDR_PANTR Androgen receptor (Gene Name=AR)

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