Structure of PDB 1lvm Chain A

Receptor sequence
>1lvmA (length=229) Species: 12227 (Tobacco etch virus) [Search protein sequence]
GHHHHHHHGESLFKGPRDYNPISSTICHLTNESDGHTTSLYGIGFGPFII
TNKHLFRRNNGTLLVQSLHGVFKVKNTTTLQQHLIDGRDMIIIRMPKDFP
PFPQKLKFREPQREERICLVTTNFQTKSMSSMVSDTSCTFPSSDGIFWKH
WIQTKDGQCGSPLVSTRDGFIVGIHSASNFTNTNNYFTSVPKNFMELLTN
QEAQQWVSGWRLNADSVLWGGHKVFMDKP
3D structure
PDB1lvm Structural basis for the substrate specificity of tobacco etch virus protease.
ChainA
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.-.-
3.4.22.44: nuclear-inclusion-a endopeptidase.
3.4.22.45: helper-component proteinase.
3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H46 D81 T146 C151 H167 S168 A169 S170 N171 F172 N174 N176 Y178 H214 K215 V216 F217 M218 K220 H54 D89 T154 C159 H175 S176 A177 S178 N179 F180 N182 N184 Y186 H222 K223 V224 F225 M226 K228
BS02 peptide A V63 F64 K65 K67 D90 V71 F72 K73 K75 D98
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1lvm, PDBe:1lvm, PDBj:1lvm
PDBsum1lvm
PubMed12377789
UniProtP04517|POLG_TEV Genome polyprotein

[Back to BioLiP]