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BioLiP

Structure of PDB 1k7a Chain A

Receptor sequence
>1k7aA (length=104) Species: 10090 (Mus musculus) [Search protein sequence]
GPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKP
KMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAM
LDVK
3D structure
PDB1k7a Structural studies of Ets-1/Pax5 complex formation on DNA.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A Y386 R391 R394 Y397 K404 Y410 Y54 R59 R62 Y65 K72 Y78
BS02 dna A L337 W375 K379 K381 M384 K388 R391 Y395 Y396 L5 W43 K47 K49 M52 K56 R59 Y63 Y64
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1k7a, PDBe:1k7a, PDBj:1k7a
PDBsum1k7a
PubMed11779502
UniProtP27577|ETS1_MOUSE Protein C-ets-1 (Gene Name=Ets1)

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